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	<title>Comments for non surgical repair</title>
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	<link>http://achillesblog.com/jeepin</link>
	<description>Just another AchillesBlog.com weblog</description>
	<pubDate>Fri, 30 Jul 2010 20:55:56 +0000</pubDate>
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		<title>Comment on PRP injection by thomas</title>
		<link>http://achillesblog.com/jeepin/2009/05/18/non-surgical-repair/comment-page-2/#comment-79</link>
		<dc:creator>thomas</dc:creator>
		<pubDate>Thu, 29 Jul 2010 20:39:01 +0000</pubDate>
		<guid isPermaLink="false">http://achillesblog.com/jeepin/2009/05/18/non-surgical-repair/#comment-79</guid>
		<description>i dont care so much about after needle
i am concerned as to how long the needle is in me
and 2  does it hurt when it is in me?
my doctor also said i cannot have any novicane or lidocane
 that i have to do it without any numbness
why/i havent a clue</description>
		<content:encoded><![CDATA[<p>i dont care so much about after needle<br />
i am concerned as to how long the needle is in me<br />
and 2  does it hurt when it is in me?<br />
my doctor also said i cannot have any novicane or lidocane<br />
 that i have to do it without any numbness<br />
why/i havent a clue</p>
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		<title>Comment on PRP injection by katie</title>
		<link>http://achillesblog.com/jeepin/2009/05/18/non-surgical-repair/comment-page-2/#comment-78</link>
		<dc:creator>katie</dc:creator>
		<pubDate>Wed, 28 Jul 2010 13:54:09 +0000</pubDate>
		<guid isPermaLink="false">http://achillesblog.com/jeepin/2009/05/18/non-surgical-repair/#comment-78</guid>
		<description>Back to report on my progress.... There was no progress at all, more of a regress! The PRP did not work for me at ALL it only made me more swollen than ever! 

I hope its working for everyone else! I haven't heard anything but praise about this procedure and am very upset it was unsuccessful for me... On to the next treatment options...</description>
		<content:encoded><![CDATA[<p>Back to report on my progress&#8230;. There was no progress at all, more of a regress! The PRP did not work for me at ALL it only made me more swollen than ever! </p>
<p>I hope its working for everyone else! I haven&#8217;t heard anything but praise about this procedure and am very upset it was unsuccessful for me&#8230; On to the next treatment options&#8230;</p>
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		<title>Comment on PRP injection by jason</title>
		<link>http://achillesblog.com/jeepin/2009/05/18/non-surgical-repair/comment-page-2/#comment-77</link>
		<dc:creator>jason</dc:creator>
		<pubDate>Thu, 22 Jul 2010 15:58:41 +0000</pubDate>
		<guid isPermaLink="false">http://achillesblog.com/jeepin/2009/05/18/non-surgical-repair/#comment-77</guid>
		<description>PRP does work but there are varying methods of prep and proper application is important. Some PRP kits attempt to isolate the platelets in plasma w/o WBCs (white blood cells) but platelet concentrations tend to be lower. 

Another method is to isolate platelets using higher centrifugal settings which causes a higher platelet concentration but leaves WBCs in the mix (may or may not be good).

In the case of planar fasciosis, you need the WBCs to help initiate the inflammatory response. However, planar fasciitis indicates inflammation is already occuring so WBCs may not be good. So, proper diagnosis w/ proper treatment could be a reason why some arent seeing the benefits. 

If you are wondering whether PRP works I will tell you that there is plenty of literature suggesting that PRP can be helpful in numerous would healing situations, and this is based on platelets containing several growth factors.  If you do a search on pubmed you will find many publications stating such.

Here is a quick review of platelet science from a colleague of mine.

"A large family of growth factors have been functionally identified in the wound healing process over the past few decades.  Of these platelet-derived growth factor (PDGF) has received significant attention in the context of wound healing.  Studies have shown that PDGF is a heterodimeric peptide that stimulates mitogenic activity in mesenchymal cells and collagen production in fibroblasts.  Transforming growth factor (TGF) has been shown to be another key participant in the dynamics of wound healing.  It markedly accelerates extracellular matrix production and stimulates granulation tissue, among other effects.  Other growth factors with known wound healing and/or growth promoting effects are fibroblast growth factor (FGF), epidermal growth factor (EGF), vascular endothelial growth factor (VEGF), and insulin-like growth factor (IGF).  Studies also suggest that there may be a synergism among some growth factors indicating that the semantics of wound healing mediated by these growth factors is quite complex, and that one specific growth factor may not be sufficient for the optimal progress of tissue regeneration.  Platelet granules are storehouses for most of the aforementioned growth factors.  Under normal wound healing circumstances, these growth factors are released when the platelets, in the vicinity of the wound, are stimulated by tissue factor and thrombin that also present in the wound.  Thus, the philosophy of using platelet concentrates to enhance wound healing stemmed from natural processes where the contents of platelets are known to be instrumental in tissue repair.   So, it is understandable that most of the current autologous products focus on platelets as their source of growth factors."</description>
		<content:encoded><![CDATA[<p>PRP does work but there are varying methods of prep and proper application is important. Some PRP kits attempt to isolate the platelets in plasma w/o WBCs (white blood cells) but platelet concentrations tend to be lower. </p>
<p>Another method is to isolate platelets using higher centrifugal settings which causes a higher platelet concentration but leaves WBCs in the mix (may or may not be good).</p>
<p>In the case of planar fasciosis, you need the WBCs to help initiate the inflammatory response. However, planar fasciitis indicates inflammation is already occuring so WBCs may not be good. So, proper diagnosis w/ proper treatment could be a reason why some arent seeing the benefits. </p>
<p>If you are wondering whether PRP works I will tell you that there is plenty of literature suggesting that PRP can be helpful in numerous would healing situations, and this is based on platelets containing several growth factors.  If you do a search on pubmed you will find many publications stating such.</p>
<p>Here is a quick review of platelet science from a colleague of mine.</p>
<p>&#8220;A large family of growth factors have been functionally identified in the wound healing process over the past few decades.  Of these platelet-derived growth factor (PDGF) has received significant attention in the context of wound healing.  Studies have shown that PDGF is a heterodimeric peptide that stimulates mitogenic activity in mesenchymal cells and collagen production in fibroblasts.  Transforming growth factor (TGF) has been shown to be another key participant in the dynamics of wound healing.  It markedly accelerates extracellular matrix production and stimulates granulation tissue, among other effects.  Other growth factors with known wound healing and/or growth promoting effects are fibroblast growth factor (FGF), epidermal growth factor (EGF), vascular endothelial growth factor (VEGF), and insulin-like growth factor (IGF).  Studies also suggest that there may be a synergism among some growth factors indicating that the semantics of wound healing mediated by these growth factors is quite complex, and that one specific growth factor may not be sufficient for the optimal progress of tissue regeneration.  Platelet granules are storehouses for most of the aforementioned growth factors.  Under normal wound healing circumstances, these growth factors are released when the platelets, in the vicinity of the wound, are stimulated by tissue factor and thrombin that also present in the wound.  Thus, the philosophy of using platelet concentrates to enhance wound healing stemmed from natural processes where the contents of platelets are known to be instrumental in tissue repair.   So, it is understandable that most of the current autologous products focus on platelets as their source of growth factors.&#8221;</p>
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		<title>Comment on PRP injection by normofthenorth</title>
		<link>http://achillesblog.com/jeepin/2009/05/18/non-surgical-repair/comment-page-2/#comment-75</link>
		<dc:creator>normofthenorth</dc:creator>
		<pubDate>Sun, 11 Jul 2010 06:05:54 +0000</pubDate>
		<guid isPermaLink="false">http://achillesblog.com/jeepin/2009/05/18/non-surgical-repair/#comment-75</guid>
		<description>When I first went to "Weight Bearing As Tolerated", my heel really complained about holding me up. Even at first in the boot, but then again in 2 shoes and barefoot, especially on hard floors, and especially-squared on rough surfaces or (God Forbid) while stepping on a phone cord or any other "hazard"!

When I told my PT, he suggeted that I sit with a golf ball under my heel and roll the ball around with my heel, as a self-deep-massage therapy. It seemed to help.</description>
		<content:encoded><![CDATA[<p>When I first went to &#8220;Weight Bearing As Tolerated&#8221;, my heel really complained about holding me up. Even at first in the boot, but then again in 2 shoes and barefoot, especially on hard floors, and especially-squared on rough surfaces or (God Forbid) while stepping on a phone cord or any other &#8220;hazard&#8221;!</p>
<p>When I told my PT, he suggeted that I sit with a golf ball under my heel and roll the ball around with my heel, as a self-deep-massage therapy. It seemed to help.</p>
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		<title>Comment on PRP injection by Gregx</title>
		<link>http://achillesblog.com/jeepin/2009/05/18/non-surgical-repair/comment-page-2/#comment-74</link>
		<dc:creator>Gregx</dc:creator>
		<pubDate>Sat, 10 Jul 2010 23:53:32 +0000</pubDate>
		<guid isPermaLink="false">http://achillesblog.com/jeepin/2009/05/18/non-surgical-repair/#comment-74</guid>
		<description>I see a lot of  of plantar fasciitis stories here. The best treatment for me was a deep tissue massage . The massage therapist, in addition to working on the rest of my body, spent a good portion of time on my feet. She really dug deep into the tendons. Having someone dig their thumbs into the bottom of your feet is not  the most pleasant feeling , especially  when you have PF!! but for some reason this helped. After about 6 sessions the  PF pain dropped off by 98%. 
Rolling my foot over a golf ball for a few minutes a day has helped keep the PF away.

Gregx</description>
		<content:encoded><![CDATA[<p>I see a lot of  of plantar fasciitis stories here. The best treatment for me was a deep tissue massage . The massage therapist, in addition to working on the rest of my body, spent a good portion of time on my feet. She really dug deep into the tendons. Having someone dig their thumbs into the bottom of your feet is not  the most pleasant feeling , especially  when you have PF!! but for some reason this helped. After about 6 sessions the  PF pain dropped off by 98%.<br />
Rolling my foot over a golf ball for a few minutes a day has helped keep the PF away.</p>
<p>Gregx</p>
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		<title>Comment on PRP injection by MLrunner</title>
		<link>http://achillesblog.com/jeepin/2009/05/18/non-surgical-repair/comment-page-2/#comment-73</link>
		<dc:creator>MLrunner</dc:creator>
		<pubDate>Fri, 09 Jul 2010 14:55:24 +0000</pubDate>
		<guid isPermaLink="false">http://achillesblog.com/jeepin/2009/05/18/non-surgical-repair/#comment-73</guid>
		<description>I've had plantar fasciitis for 3 yrs. Pursued all modes of treatment for it, ie Endoscopic fasciotomy, ESWT, phys therapy, cortisone, etc. with no perm relief. In Nov '09, rec'd 1st PRP injection; helped tremendously. In May '10, rec'd 2nd; didn't help at all. In June '10, rec'd 3rd and final PRP injection from an orthopedist; this time, using ultrasound (1st MD did not use ultrasound for 1st 2 injections.) Too early to tell if it's helped; still in the walking boot. Good to read other's experience here. Given 1st one helped, I"m hopeful this third one will as well.</description>
		<content:encoded><![CDATA[<p>I&#8217;ve had plantar fasciitis for 3 yrs. Pursued all modes of treatment for it, ie Endoscopic fasciotomy, ESWT, phys therapy, cortisone, etc. with no perm relief. In Nov &#8216;09, rec&#8217;d 1st PRP injection; helped tremendously. In May &#8216;10, rec&#8217;d 2nd; didn&#8217;t help at all. In June &#8216;10, rec&#8217;d 3rd and final PRP injection from an orthopedist; this time, using ultrasound (1st MD did not use ultrasound for 1st 2 injections.) Too early to tell if it&#8217;s helped; still in the walking boot. Good to read other&#8217;s experience here. Given 1st one helped, I&#8221;m hopeful this third one will as well.</p>
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		<title>Comment on PRP injection by Claudia</title>
		<link>http://achillesblog.com/jeepin/2009/05/18/non-surgical-repair/comment-page-2/#comment-72</link>
		<dc:creator>Claudia</dc:creator>
		<pubDate>Thu, 01 Jul 2010 20:30:14 +0000</pubDate>
		<guid isPermaLink="false">http://achillesblog.com/jeepin/2009/05/18/non-surgical-repair/#comment-72</guid>
		<description>Lisa from February 22, 2010.

How are you progressing?  I had PRP in my right elbow 2 weeks ago and had basically the same reaction as you.  Please tell me there is hope and it was all worth it.</description>
		<content:encoded><![CDATA[<p>Lisa from February 22, 2010.</p>
<p>How are you progressing?  I had PRP in my right elbow 2 weeks ago and had basically the same reaction as you.  Please tell me there is hope and it was all worth it.</p>
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		<title>Comment on PRP injection by jeff</title>
		<link>http://achillesblog.com/jeepin/2009/05/18/non-surgical-repair/comment-page-2/#comment-71</link>
		<dc:creator>jeff</dc:creator>
		<pubDate>Tue, 29 Jun 2010 01:53:17 +0000</pubDate>
		<guid isPermaLink="false">http://achillesblog.com/jeepin/2009/05/18/non-surgical-repair/#comment-71</guid>
		<description>I recieved a PRP injection to my right achilles four days ago. Prior to the injection my doctor put me in a boot for a week to try to calm the area down a bit.  The injection was not bad at all. The blood draw was the hardest part of the procedure as they couldn't seem to find a vein.  It was extremly sore through the night and really bad in the morning. But after that,  the pain has gone away and the swelling is nearly gone. It seems from what I've been reading, that the pain associated with the procedure is very much an individual experience. My doctor emphasized heavily that I was to be inactive as much as possible for the first week to allow the Platlets to get in there, swell the area, and activate the bodies healing mechanisms. I will then be in the boot for three to four weeks.  My doctor was honest in telling me that this procedure will not work for everyone, but he sees about a 90% success rate in his practice.  16 years ago I ruptured the left achilles. Even if this takes six months to repair , it beats a full blown achilles rupture recovery.</description>
		<content:encoded><![CDATA[<p>I recieved a PRP injection to my right achilles four days ago. Prior to the injection my doctor put me in a boot for a week to try to calm the area down a bit.  The injection was not bad at all. The blood draw was the hardest part of the procedure as they couldn&#8217;t seem to find a vein.  It was extremly sore through the night and really bad in the morning. But after that,  the pain has gone away and the swelling is nearly gone. It seems from what I&#8217;ve been reading, that the pain associated with the procedure is very much an individual experience. My doctor emphasized heavily that I was to be inactive as much as possible for the first week to allow the Platlets to get in there, swell the area, and activate the bodies healing mechanisms. I will then be in the boot for three to four weeks.  My doctor was honest in telling me that this procedure will not work for everyone, but he sees about a 90% success rate in his practice.  16 years ago I ruptured the left achilles. Even if this takes six months to repair , it beats a full blown achilles rupture recovery.</p>
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		<title>Comment on PRP injection by Annette</title>
		<link>http://achillesblog.com/jeepin/2009/05/18/non-surgical-repair/comment-page-2/#comment-70</link>
		<dc:creator>Annette</dc:creator>
		<pubDate>Mon, 28 Jun 2010 22:42:35 +0000</pubDate>
		<guid isPermaLink="false">http://achillesblog.com/jeepin/2009/05/18/non-surgical-repair/#comment-70</guid>
		<description>I just recieved a PRP shot in my quadricep tendon on fri, 3 days ago. It hurt pretty bad during shot, but only took 30 seconds. My dr. didnt give me any after care details like I hear about you guys doing. My quad is pretty sore now, and I am trying not to bend it cause that hurts and i want it to heal. I had a partial tear in my quad tendon for the last year. I am open to any advise. Thanks</description>
		<content:encoded><![CDATA[<p>I just recieved a PRP shot in my quadricep tendon on fri, 3 days ago. It hurt pretty bad during shot, but only took 30 seconds. My dr. didnt give me any after care details like I hear about you guys doing. My quad is pretty sore now, and I am trying not to bend it cause that hurts and i want it to heal. I had a partial tear in my quad tendon for the last year. I am open to any advise. Thanks</p>
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		<title>Comment on PRP injection by mikek753</title>
		<link>http://achillesblog.com/jeepin/2009/05/18/non-surgical-repair/comment-page-2/#comment-69</link>
		<dc:creator>mikek753</dc:creator>
		<pubDate>Mon, 28 Jun 2010 22:36:55 +0000</pubDate>
		<guid isPermaLink="false">http://achillesblog.com/jeepin/2009/05/18/non-surgical-repair/#comment-69</guid>
		<description>Katie,

Please, keep us posted about your PRP progress.
I wasn't convinced about PRP and my Doc. nether - so I didn't get any.
My logic based on:
1. PRP cause inflammation that is explained as repairing process - I have had enough inflammation that no need to cause more that it was / is
2. PRP on tendons wasn't proven as it was for other tissue repair - especially for tissues that had not have inflammation around it - so PRP triggers that process</description>
		<content:encoded><![CDATA[<p>Katie,</p>
<p>Please, keep us posted about your PRP progress.<br />
I wasn&#8217;t convinced about PRP and my Doc. nether - so I didn&#8217;t get any.<br />
My logic based on:<br />
1. PRP cause inflammation that is explained as repairing process - I have had enough inflammation that no need to cause more that it was / is<br />
2. PRP on tendons wasn&#8217;t proven as it was for other tissue repair - especially for tissues that had not have inflammation around it - so PRP triggers that process</p>
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